"By donating Jonah’s tumor tissue for research, the Amor family gave cancer scientists an incredible gift. “We could take different points and actually see what was changing in the tumor in response to treatments, in response to radiation over time, including both brain disease and then also metastatic disease in the lung, which is incredibly rare,” Greenfield explained. “We were really fortunate to pair with this amazing kid and his parents who continued to come back and continued to put their faith in us.” Greenfield’s lab used Jonah’s tumor tissue to establish the first patient-derived cell line for ETMR and then created an animal model to study the disease further. Greenfield partnered with Craig Thomas, PhD, at the National Institutes for Health, to screen Jonah’s cells against hundreds of drugs, revealing several promising candidates for unique compounds and drug combinations that could be tested in an animal model."
https://childrenscancer.org/how-one-boys-cells-could-power-new-treatments-for-etmr/
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